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colchicine - WordReference English dictionary, questions, discussion and forums
colchicine: [noun] a poisonous alkaloid C22H25NO6 that inhibits mitosis, is extracted from the corms or seeds of the autumn crocus (Colchicum autumnale), and is used especially in the treatment of gout and to produce polyploidy in plants
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Pain, tingling, or numbness in the hands or feet
Use of colchicine for treatment of gout flare is not recommended in patients with renal impairment who are receiving the drug for prevention of gout flares
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Colchicine is an alkaloid with the formula C22H25NO6 (Figure 1), including three rings
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easy bruising, unusual bleeding, feeling weak or tired
8 mg daily
Use colchicine + asciminib CV EVENT RISK REDUCTION: consider alternative or monitor CBC; GOUT or FMF: contraindicated in pts w/ renal or hepatic impairment; otherwise, use alternative or monitor CBC and consider decr
It is used in the treatment of gout and to create polyploid plants by inhibiting chromosome separation during meiosis
The Colchicine Cardiovascular Outcomes Trial (COLCOT), a randomized, double-blinded trial, found a lower risk for ischemic cardiovascular events with 0
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These are types of arthritis caused by a buildup of crystals in the joints
Diarrhea, nausea, cramping, abdominal pain, and vomiting may occur